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Which moieties are considered problematic?
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Also, pyridopyrimidine moiety was considered as the best-known tyrosine kinase inhibitor for the treatment of endless myelogenous leukemia and medication resistance rises by enhancement of the improvement of a transformation [19].
21 An electron-rich situation with spin-density localized at the Fe cluster moiety is considered to be a crucial prerequisite for photo- and electrocatalytic hydrogen production.
In the SOCM catalysts, (SiO 3SiO− +NR4) moieties located at the accessible sites are considered to play some important roles.
The active sites of the SOCM catalysts are considered to be SiO− moieties located on the pore-mouth.
These are considered to be basic moieties with syringyl units from precursor sinapyl alcohol that are components of the lignin structure [ 3].
Metallic radionuclides usually feature prolonged decay times and, thus, they are considered to be better matches for the previously-mentioned targeting moieties, having long biological half-lives.
Both sp2 and sp3 carbon-bound hydroxyls are considered potential sites of O-glycosylation with a randomly selected sugar moiety.
Membrane-bound cytochromes c are considered to bind to the cellular membrane via a diacylglyceryl-cysteine moiety.
Cyclopurine nucleosides are considered tandem lesions in that concomitant damage is produced in both the base moieties and the sugar (Dizdaroglu 1986).
Inhibitors of these metalloproteinases are considered as potential therapeutic agents to protect cartilage degradation, and many active site-directed inhibitors with a zinc-chelating moiety have been developed.
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