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The combined analysis of structural and functional networks has begun to reveal components or modules with distinct patterns of connections that become engaged in different cognitive tasks.
Instead, it can be deconstructed into three separate microcircuit modules with distinct V2a interneuron subclasses driving slow, intermediate, or fast motoneurons.
Using this approach to analyze tetratricopeptide repeat modules that contain three tandem repeats (3TPRs), we identify two classes of 3TPR modules with distinct structural signatures that are correlated with different sets of functional residues.
We robustly grouped these transcripts by K-means clustering into modules with distinct temporal expression patterns, shared regulatory motifs, and biological functions.
For example, variation in low-level global properties of the neural substrate may induce a general factor underlying quantitative differences in high-level modules with distinct functions and operating principles.
The network contained eight modules with distinct expression patterns.
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To uncover epigenomic and genomic patterns, CpG loci are clustered into nine modules associated with distinct chromatin and genomic signatures based on terms of biological function.
Domains are sequence fragments that encode protein modules with a distinct structure and function, the basic building blocks of proteins.
The existence of hierarchical modularity of bigram networks necessarily implies that some domains in the network appear more "versatile" than others and serve to connect the otherwise distant modules with rather distinct functions.
Further investigation revealed that these modules were associated with distinct levels of gene expression and dominant biological functions.
We integrated transcriptomic associations and cell wall metabolism for 29 rice tissues and found that certain co-expressed gene modules are positively correlated with distinct cell wall characteristics.
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