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Thus, the overview network is good for a high-level overview of between-cluster genetic interactions between modules as well as a sense of how many and which modules were discovered.
Indeed, in Stensola et al. (2012), 4 5 modules were discovered in recordings spanning up to 50% of the dorsoventral extent of MEC; extrapolation gives a total module number consistent with our estimate.
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In summary, finding densely connected regions in genetic interaction networks alone should yield that the modules are quite trustworthy while not necessarily all modules are discovered.
The module was discovered intact, separated from other wreckage pieces, embedded in about 20 cm of soil, and was also sent for analysis by the TSB in Canada.
In one case, a type II toxin-antitoxin module was discovered on the opposite strand of a gene currently annotated as BCAL1704, a conserved hypothetical protein.
In the mesoderm module, however, no non-interactions were discovered.
Several known cis-regulatory elements were discovered in the promoters of Module 1 genes (Additional file 14: Table S5).
However, in some modules where more than one function was identified, meaningful biological relationships between these functions were discovered.
Important fossils were discovered.
Multiple conserved molecular signaling modules have been discovered through powerful genetic screening.
While several effector modules have been discovered for H3K4me3 and H3K9me3, many other marks have few or no known effectors.
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