Sentence examples for modules were annotated from inspiring English sources

Modules were annotated by using WEB-based GEneSetoAnaLysis Toolkit (WEBGESTALT) to perform KEGG pathway and GO analysis [ 22, 32].

The nine structurally compact CT-PPI modules were annotated for oxidative phosphorylation (Table 3), a critical metabolic pathway that produces adenosine triphosphate.

In the fifth phase, the modules were annotated using KEGG-pathway and Gene Ontology enrichment analysis, in order to obtain a better understanding of the implications of priming for microglia function.

Again, the eQTL modules corresponding to these eQTL hotspots shared a large fraction of member genes, and many of the genes that are shared by these four eQTL modules were annotated with common GO terms.

Genes in both modules were in general annotated to similar gene ontology terms and, in particular, the majority of genes in both modules were annotated to the term M-phase (Additional file 6).

Interestingly, several modules were annotated for cell differentiation and survival pathways such as 'Wnt signaling', a pathway suspected to have a role in HD pathogenesis [ 46], 'apoptosis signaling' and 'integrin signaling', suggesting that such pathways might be targeted for therapeutic intervention in HD.

Two Arabidopsis AFP2 (ABI FIVE BINDING PROTEIN 2) modules (AM606236 and AM604130) are shown in Figure 4A and B. The interaction prediction methods linking each node in these modules are annotated on the edges shown in the diagrams illustrating that there is significant evidence linking each of these proteins to the other proteins in the module.

For example, those genes in the brown module were annotated as being involved in response to stimulus, while those in the blue module were annotated as functioning in cell differentiation.

Several members of the co-expression module are annotated with the KEGG classifications cytokine-cytokine interaction and Toll-like receptor signaling.

Each module was annotated to Gene Ontology using the Bioconductor package GOstats [ 46], using the hypogeometric test.

Twenty-three of the 37 genes in this module are annotated to the GO category 'conjugation' (GO 0000746, p = 3.98E-29).