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Jha, A. K. et al. Network integration of parallel metabolic and transcriptional data reveals metabolic modules that regulate macrophage polarization.
Gene networks can act as information-processing modules that regulate cellular metabolism, cell division, and differentiation.
An important paper demonstrating that mROS are necessary for hyperinflammatory responses in patients that carry mutations in the gene that encodes TNF receptor type 1. Jha, A. K. et al. Network integration of parallel metabolic and transcriptional data reveals metabolic modules that regulate macrophage polarization.
Collagens contain cryptic polypeptide modules that regulate major cell functions, such as cell proliferation or death.
Mainly through genetic screens, the Drosophila community has largely contributed to the molecular dissection of the signaling modules that regulate expression of immune genes following infection.
PDZ domains are protein interaction modules that regulate targeting and trafficking of cell surface proteins.
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We identified three transcription factors as the conservative modules that regulated the xylose metabolism regardless of which xylose pathway was used and which host the xylose pathway was expressed in.
We next focused on identifying candidate genes in the brown module that regulate the response to atherosclerotic and inflammatory stimuli.
The part in question is an ignition module that regulates current to the spark plugs.
The IO, as the sole source of CFs, has been regarded as an important module that regulates the behavior of PCs.
At the molecular level, interactions between active nodes involve one SSTF protein binding a cis-regulatory module that regulates expression of the transcript of a target SSTF.
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