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In particular, vertices with similar properties or function have a higher chance to be linked to each other than random pairs of vertices and tend to form highly cohesive subgraphs, which are called communities (also modules or clusters).
In addition to the two large modules containing genes encoding muscle structural proteins, a number of smaller modules or clusters of genes also contain a subset of muscle structural proteins (Table 2).
Finding dense subnetworks (ie, modules or clusters) Figure 6A.
This program created modules or clusters of highly correlated genes in each tissue separately.
Modules or clusters are then defined using the Markov Clustering algorithm (MCL) and both the network and clusters visualised using a powerful 3D network rendering engine.
The resulting modules for each network were related with the gestational age to identify modules, or clusters, of co-expressed genes with increasing or decreasing expression pattern.
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On the other hand, the model-assisted methods differ mainly in their module (or cluster) detection techniques.
Finally, we partitioned the GBM network into network modules or communities — clusters of network nodes joined together in tightly knit groups, between which there are only looser connections [18].
These modules (or gene clusters) were selected for further analyses.
As such, it is doubtful that isolated modules, or dense clusters, will contain high-degree proteins.
Several algorithms and bioinformatic tools have been proposed for partitioning the network into structural modules, or for clustering sub-network modules within an informative network [15,16].
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