Sentence examples for modules of unknown from inspiring English sources

The first identified member, CpGH84A, corresponds to the μ-toxin whose modular architecture includes an N-terminal catalytic domain, four family 32 carbohydrate-binding modules, three FIVAR modules of unknown function, and a C-terminal putative calcium-binding module.

Several modules of unknown or indeterminate function were also found associated with subtilisin-like proteins in prokaryotes (Table 3; Additional file 1).

It is noteworthy that four modules of unknown function are fused to the N-terminus of one of the AA5_1 contig07281.

In others, CBMs are the only identifiable modular type, and many others contain modules of unknown function; hence these latter dockerin-containing proteins cannot currently be classified as enzymes.

The cellulosomes produced by R. cellulolyticum are composed of a single primary scaffoldin which contains a powerful cellulose binding module, two X2 modules of unknown function(s) and eight copies of a receptor domain, called the cohesin which strongly interacts with a complementary module borne by the catalytic subunits and termed the dockerin [ 13, 14].

The smallest and most extensively studied member, CpGH84C, comprises an N-terminal catalytic domain with β-N-acetylglucosaminidase activity, a family 32 carbohydrate-binding module, a family 82 X-module (X82) of unknown function, and a fibronectin type-III-like module.

This proteolytic machine consists of a barrel-shaped peptidase capped by a large regulatory particle, which contains a heterohexameric AAA + unfoldase as well as several structural modules of previously unknown function.

Cellulases are often modular multi-domain enzymes composed of carbohydrate-binding modules or predicted domains of unknown function (Bergquist et al. 1999).

Those maps should provide an useful starting point for predicting functional interactions and modules, and the function of unknown proteins.

As these modules contain many genes of unknown function, their co-occurrence with genes with known function related to specific traits may be useful for annotation purposes.

It will be interesting in the future to determine whether this type of unknown module functions as a CBM and modulates the activity characteristics of the GH9 catalytic module.