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Exact(6)

These findings provide additional evidence that the joint expression of these modules may play a relevant role in human aging.

It is, however, tantalizing to speculate that a temporal and spatial assembly of different protein modules may play similar roles in mammalian CME.

The distance between adjacent target sites of miRNAs in the same miRNA modules may play critical roles in target mRNA downregulation (Doench and Sharp, 2004; Saetrom et al., 2007).

Since Rho-GTPases and the MAPK signalling pathways had been characterized as being involved in the regulation of cell-wall biosynthesis in S. cerevisae and some other filamentous fungi, these signal transduction modules may play roles in cell-wall biosynthesis and be involved in the regulation of isotropic growth.

The most recent results from this systematic dissection of the bridge helix, published in BMC Biology by Weinzierl [ 7], suggest that kinking of the helix at or adjacent to segments that contact the interconnected network of RNA polymerase modules may play a more important role in the nucleotide-addition cycle than contacting the template base or looping to generate a translocation pawl.

Interestingly, the conserved TFs in xylose metabolism, Gcn4p, Rpn4p, and Yap1p, were also found among the key modules responsible for the host dependence, suggesting that the same regulatory modules may play different roles in the transcriptional regulation of carbon metabolism in different hosts of S. cerevisiae.

Similar(54)

This finding suggests that the non-catalytic module may play a role in additional biological processes independent of the catalytic module.

This module may play a role in synaptic remodeling, as neuronal MHC class I molecules were recently found to regulate synapses in the central nervous system in response to activity [ 40].

In the example of the two modules in the general cancer cluster in Figure 2a and 2b, each module may play different roles in the regulation of specific biological processes -- cell division and nucleic acid metabolism, respectively; the latter is clearly required for cell division.

Although the mechanism by which each of these proteins attack cellulose has yet to be resolved, the observation that most of these swelling or delaminating agents contain a (potential) carbohydrate-binding surface may indicate that this binding module may play an important role in this non-hydrolytic amorphogenesis activity.

Thus, the genes in the Violetdiff module may play a direct role in enhancing muscle development as they were highly connected in the high muscling sire group and correlated with EBVs for this group but not in the low muscling group.

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