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First, each mRNA is assumed to be a target of all miRNAs assigned to the modules it belongs to as long as they are predicted to regulate it.
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In terms of information diffusion - and much like in [39] - we explore whether community structure (and in particular, the relation of a seed node with the module it belongs to) has an impact on the success of a cascade.
Together these components provide a concise description of the joint distribution over all genes in G, such that each gene depends on the parents of the module it belongs to; see (Segal et al., 2005).
The Nbcs(i) of a node i is the relative betweenness centrality but calculated only within the module s which it belongs to.
Thus, a node whose role is unknown can be annotated with the functions appearing most frequently in the module(s) to which it belongs.
A Banach module which belongs to this class is called a BSE.
The payload packing problem of a satellite module (SM3P) belongs to a complex engineering layout and combinatorial optimization problem.
If an (R -module (M) belongs to some (zeta _{alpha }), then the least such (alpha ) is called the couniseR -modulension of (M), denoted belongsdim((M)).
If an (R -module (M) belongs to some (zeta _alpha ), then the least such (alpha ) is the uniseR -modulension of(M), denoted u.s.dim((M)).
Table 8 shows the highly scored modules that were analysed with respect to their associated functional groups, pathways and GO Terms From this table it can be observed that the modules identified belonged mostly to the Apoptosis and Survival, Immune Response, DNA Damage, Development, and Transcription functional groups.
Note that for cancer type with two different datasets, if a mutated gene in core modules only belonged to one of them, its number of cancer type N was defined as 1/2.
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Justyna Jupowicz-Kozak
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