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There exists overlap among gene modules in large real networks.
We will use k-clique algorithm [ 18], which is an effective and deterministic method for uniquely identifying overlapping modules in large real networks.
Crucial considerations in assessing the performance of modularity optimisation approaches are: (i) the scale and optimality handled by modularity optimisation methods and (ii) the resolution limit problem for small-size modules in large networks.
Compared with other module-detecting algorithms, such as the markov clustering method, the SA algorithm performs better in detecting modules in large scale metabolic networks and the detected modules are more biologically meaningful [ 56], since the SA algorithm is less sensitive to noise such as experimental error or incomplete data.
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The identification of immune-related modules in large-scale transcriptional regulatory networks can reveal the mechanisms by which exposure to a pathogen elicits a precise phenotypic immune response.
Signaling modules are important for modularization of the EGFR signaling pathway as well as more generally for reuse and integration of modules in larger system models.
Cells may grow to higher densities in small modules than in larger modules because transport of nutrients to and from the center of a module is limited by diffusion in modules above a certain size.
The reason for the slow power growth of traditional Si solar modules lies in large consumption of materials and energy, high labor intensiveness and, as a consequence, in low productivity and high cost of modules with acceptable PV conversion efficiency for mass production [4, 5].
We also identified novel versions of the HEPN domain that comprised the C-terminal modules in a large group of COG1517-related proteincludinguding Csx1 and Csm6 subfamilies), which are encoded by genes found in a subset of the CRISPR-Cas loci (Table 1) [ 4, 57].
The songs on "Biophilia" will also be released as apps — one for each song, to be sold as modules in a larger app for the entire album — for the iPad and iPhone.
This article addresses the problem of fault propagation between software modules in a large-scale control system with object oriented architecture.
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