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The selected reporter enzymes and modules from each subnetwork were more closely associated with CHD.
Functional enrichment was performed for each of the modules from each GIL.
As to biological significance, the accuracy and separation are used for evaluating the correspondence between complexes and modules from each method [ 28].
The Markov Clustering algorithm (MCL) [ 31] was used to identify modules from each of the combined networks for the four species.
Significantly enriched Biological Processes (BP; p < 0.01; WebGestalt software [ 8]) of the positively correlated top modules from each brain region are shown in Additional file 6: Table S2.
In the time-based analysis, we have detected 50 functional modules from each stage of AD group, and there are 188 modules are inserted into our observed module set after removing the duplicate modules.
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It is for this reason that the analysis was carried out only on the conserved EGF module from each of these diverse ligand precursors.
Table 4 lists the final number of modules identified from each brain region pair, as well as the number of "core" modules and "core" genes for each brain tissue (i.e. those present in the majority of pair wise comparisons).
We list the final number of modules identified from each brain region pair, as well as the overall numbers of core modules and core genes for each region.
For a complex trait comprising several relatively independent modules, hybridization may however simply generate new phenotypes, by combining into a new mosaic modules inherited from each parental groups and parts intermediate with respect to the parental groups.
This was a radical idea as the established notion at the time was that the brain is made up of independent modules, insulated from each other and hardwired to a specific function.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com