Taken together, FMB provides theoretical evidences for the possible correlations among metabolic modules in response to the perturbation, as exemplified by cluster 1, 29, and 44 in this study.
In this study we show that it is possible to evolve the functionality of binders based on this scaffold as exemplified by one such module, XG-34 specific for non-fucosylated xyloglucan [ 14] while preserving its specificity for xyloglucan.
Other gene modules comprise genes that augment a specific pathway function, as exemplified by aflR/aflS, the pathway-specific transcription activator and enhancer [ 59], and aflX/aflY, the genes required for the conversion of versicolorin A to demethylsterigmatocystin [ 60].
The fusion of modules presumably increases pathway efficiency, either by locally concentrating sequential intermediates or, as exemplified by the fatty acid synthase complex, directly channeling intermediates from one active site to the next.
As exemplified by Russell Brand.
Smooth transitions are very possible, as exemplified by successful companies like LinkedIn and eBay.
As exemplified by a series of silica structures that are known as clathrasils.
