Sentence examples for modules as defined from inspiring English sources

Hundreds of functional modules, as defined by Gene Ontology, were associated with conserved expression patterns but bear no overt relationship to ESC development, suggestive of new mechanisms critical to ESC pluripotency.

We first asked how modules, as defined by FCSs, relate to conventional biochemical pathways, the classical functional modules of metabolism.

The application of the coherence index to the functional modules as defined by KEGG pathways showed that only 57% of them presented a correlation index greater than 95 (see Figure 1A).

Thus, it is urgent to take a new approach that accounts for the non-discrete nature of the functional modules as defined by the most commonly used functional annotations (GO and KEGG).

The aim of the manuscript was, on one hand to show the discrepancy between functional modules as defined in some popular repositories (GO and KEGG pathways) and real co-expressing modules and, on the other hand, to propose a new vision of such modules that combines the original definition of the function with the actual dynamics of co-expression.

We next observed that core biological modules, as defined using pathway analysis, designated lymphoid (B cell- and plasmablast-dominated), myeloid (macrophage and NF-κB process dominated) and fibroid (comprising hyperplastic but pauci-immune tissues) could be surveyed across multiple RA patient synovial tissue cohorts to identify reproducible RA phenotypes.

It is noticeable that in most ε-species, difE is genetically linked to the recombinase-encoding gene, the pair corresponding to an individual genetic module, as defined by Le Bourgeois et al. for difSL and xerS (Table 2) [23].

Please note that the term transcriptional module as defined here is closely related to the term regulatory module.

BP and CC are examples of biological processes and cellular localizations terms respectively, which are highly over-represented in each module, as defined in the GO.

In order to do so, we have derived, for each functional module as defined in GO and in KEGG, a co-expression (or coherence) index which could be used to assess the strength of its internal correlation.

Differential correlation was calculated as the absolute value of the difference between PCC after day 0 and PCC at day 0 in the module as defined on day 0. The average SD of each gene among replicates in each time point or cellular state was calculated.