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It is worthwhile to note that other FN modules are likely involved in fibril formation.

These modules are likely involved in core synaptic and regulatory pathways that are affected in both ID and ASD.

We speculate that these nodes spreading among the modules are likely to exercise different functions as compared with those within the modules.

Interactions between these two modules are likely to be critical for intramembrane charge movements in the assembled four-repeat channel and for coupling the movement of the S4 gating charges to the opening of the RyR1 channel.

The fact that these modules are enriched for ID genes, lncRNAs, and known pathways in ID disorders suggests that these modules are likely essential contributors to normal cognitive development.

It also confirms that, when using condition-free networks across a large number of arrays, tissues and conditions, the modules are likely to be associated with universal and essential cellular processes shared across organisms.

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Similar(52)

These modules were likely regulated by NH4+-N.

Just as gene duplication is now regarded as a key substrate for genome evolution, this duplication of functional, regulatory modules is likely to have provided a rich source of phenotypic variation.

To assess whether the predicted candidates especially the miRNA modules were likely functional, we studied the overlap of their target genes with known pathway genes or gene sets of known functions.

The recent identification of a histone binding motif in the ubiquitin-binding RING finger proteins RNF168 and RNF169, which confers specificity for ubiquitylated histones, suggests that bipartite recognition modules is likely a conserved feature in the ubiquitin system (Panier et al. 2012).

atBioNet begins from the hypothesis that proteins/genes in the same module are likely involved in the same biological functions or processes.

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