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For the periodic contractions motility module, we observed a temporal extent of ∼15 s., temporal oscillations with a period of ∼18 s, and lateral propagation of ∼1.5 µm/s.
With completion of the CKD module, we observed a significant improvement between pre-test and post-test scores.
In the predicted functional module we observed Pigpa1 [BROandPigpb13612] and Pigpb1 [BROAD:PIthe06376], the alpha and beta subunit of the heterotrimeric G-protein.
Similar to the brown module, we observed that the intramodular connectivity and GS were highly correlated in the blue module (cor = 0.49, p = 1.00 × 10−90), as shown in Fig. 6b.
When presenting sentences to the theta module, we observed a consistent theta burst within 50 ms following syllable onset followed by a locking of theta oscillations to theta acoustic fluctuations in the speech signal.
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In this module, we observe again a clear positive correlation pattern between miR-200a and the module genes expression, suggesting an indirect regulatory circuit between miR-200a and module 25 genes (Figure 2c and Figure 3a and 3b).
As expected from the analysis of the IRE1 α module, we observe that ATF6 amplifies both the basal and the maximal folding capacity.
In the ectoderm module, we observe that nhr-25 and elt-3 do not regulate lin-26; elt-1 does not regulate nhr-25; and lin-26 does not regulate elt-3.
While this is good evidence of that densely connected biclusters indeed reliably reflect functional modules, we observed some further interesting phenomena: Our baseline method, which operates on interaction network data only, achieved respectable enrichment (ER) values (see Table 1 and 2), which underscores that connectivity is a valuable concept when screening interaction network data.
After examining all 335 modules, we observed that 181 (54.2%) modules had no common members with any other modules.
Although the composition of co-expression modules is different from that of co-methylation modules, we observed strong correlations of expression and methylation module eigengenes.
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Justyna Jupowicz-Kozak
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