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In the Turquoise module, we identified 59 hub genes, including 40 protein coding genes and 19 lncRNAs (Sup Table 4).
In the Gray module, we identified 29 hub genes, including 22 protein coding genes and 7 lncRNAs (Sup Table 5).
In additional to the canonical SMAD mediated TGF β signaling module, we identified two interesting modules centered on SOX4 and TGFBI (GENE ID 7045).
For each WGCNA module we identified the most closely matched MCLUST module, and vice versa.
The RNA splicing module we identified contains several genes that are individually strongly associated with survival.
Within the cardiac module, we identified eight genes associated with phenotypes relating to cardiac disease in cats.
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We assessed the genetic overlap between these 7 morphologic QTLs and the yeast eQTL modules we identified.
Thus, it is likely that the IR-module we identified previously [ 15] reflects the combined high and low activation of Th1 and TGFB pathways.
Figure 2 shows the network with five highlighted subnetwork modules we identified (Louvain method [ 38]).
Moreover in each of these sub-networks (or functional modules) we identified some hub proteins.
In the 108 modules, we identified the 'hot links' that are essential for PCW synthesis.
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CEO of Professional Science Editing for Scientists @ prosciediting.com