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Each module was represented as a vector of fractions of upregulated genes in each cell type.
The expression profile of a given module was represented by its first principal component (module eigengene) which can explain the most variation of the module expression levels.
The entire Head module was represented as a rigid body (based on the X-ray structure PDB 4GWP), with the exception of the unmodeled N-terminus of Med17 (1 181), the last 103 residues of Med6, and other missing regions, all of which were represented as flexible strings of beads.
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Modularity results for the most representative subject are shown in brain space, where each module is represented by a different color (Figure 8).
The behavior of each module is represented as a sequential concurrent hybrid discrete event system.
A block diagram of our implementation is given in Figure 3, where each module is represented with a block.
The first module is represented by a polydimethylsiloxane (PDMS) microreactor that is exploited for real-time polymerase chain reaction (PCR) and, thus, is suitable for detecting the presence of virus.
The highly correlated module genes of a given module are represented and summarized by their first principal component (which is referred to as the module eigengene).
The former module is represented by the mutual activation of Oct4 and Sox2, whereas mutual inhibition of the ME and ECT genes represents the latter module [18].
Each module is represented as a pie chart, where the size of each slice is proportional to the fraction of reactions that belong to the corresponding, pre-assigned canonical (textbook) grouping.
As seen in the diagram, the abstracted version of the Grb module is represented by two edges from (EGF-EGFR* 2-GAP EGF-EGFR* 2-GAPGAP-Shc*-Grb2-Sos and (EGF-EGFR* 2-GAP-Grb2-Sos.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com