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The first module was related to inflammatory processes.
The second module was related to immune activity.
The third GO module was related to meiosis I (GO 0007127).
The second step was to consider how, within each group (WLA, PWK, F1 and F2) the variation in one module was related to variation in other modules.
Two complementary approaches were used to determine if the variation in one module was related to the variation in another one [ 50].
Gene ontology enrichment tests (see Methods) revealed that the grey60 and pink modules were related to immune functions whereas the darkorange module was related to signalling processes (Benjamini-Hochberg corrected p-value < 0.05).
Similar(52)
The second module is related to the discretization of the problem which leads to the linear system.
At least eight genes in this module were related to PCD.
Most of the genes of this module are related to tumor necrosis factor (TNF), an inflammatory cytokine.
These observations make it tempting to speculate that this module is related to processes in VAT-specific undifferentiated adipocytes.
One module was defined to be enriched in starch metabolism; 9 out of 10 genes contained in this module were related to starch metabolism.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com