To confirm whether or not the two modules in the CCA network have distinct functions, the enriched molecular functions (MFs), biological processes (BPs), and cellular components (CCs) for genes in the two modules were identified using the DAVID software [23] and setting all cancer genes in the two modules as the background population.
We focus on whether k-clique algorithm can find coexpression gene modules from the background of noise.
The testing gene lists were genes in the conserved modules, and the background list was the expressed major isoforms in PAG or cortex.
To determine how well our method detects RME modules over the background noise of passenger mutations, we ran experiments on synthetic data using several different parameter sets.
The temporal differencing approach [19] involves three important modules: block alarm module, background modelling module and object extraction module (see Figure 2).
A round mask with a diameter of 30 pixels for the small subunit, or 40 pixels for the large subunit was used during CCC computation to select the target module while excluding the background noise and the signal from the non-target module.
Real-time data storage module runs in the background.
The second measure is to find GO terms that are over-represented in any given module, relative to the background population of genes.
And then we would remove the module genes from the background network after it is done, e.g., the nodes A, B, C, and D would be removed from the network and, thus, from further analysis.
Table 2 Examples of role list Role Value Description Allow-attach-debugger Boolean Debugger can be attached to module Allow-save-to-X Boolean Output can be saved in the storage X Allow-open-application Boolean In module, an application can be opened Allow-perform-background Boolean Module can run in the background Create-child-process Integer The number of child processes that a module can create.
