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The weight indicates the importance of a gene set to a module, relative to other gene sets in that module.
We did similar analyses to determine the distance preference of CRMs of a motif module relative to the transcription start (stop) sites.
The 2D class averages highlight the globally dynamic nature of the VPS34 HELCAT module relative to the rest of the complex.
The only structural changes in the IP6-bound PH-TH module, relative to the apo- or IP4-bound PH-TH module, are in the loop regions.
The second measure is to find GO terms that are over-represented in any given module, relative to the background population of genes.
To understand how signed WGCNA is better able to separate genes into functional modules in the Ivanova data set, we plotted genes in the signed black or turquoise module relative to the unsigned turquoise module eigengene (Additional File 10).
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BMCs fix the modules relative to the VV and manage the current flow.
To do this, in Year 1 we measured the performance of students who completed the interactive modules relative to those who completed non-interactive alternative assignments.
These differences in quaternary arrangement of Kunitz modules relative to the serine proteinase moiety result in large differences when compared to the thrombin·ornithodorin complex, as we discuss below.
The bifunctional enzyme was divided into its individual FtHPPK and FtDHPS subdomains, searching first for the FtDHPS module, and the appropriate positioning of the two modules relative to the intra-domain linkage validated our eventual MR solution.
A positive SI indicates that the experiment's positive gene list has higher correspondence with stemness-on compared to stemness-off modules relative to the experiment's own negative gene list.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com