Sentence examples for module network approach from inspiring English sources

Extensive simulations on artificial data and application of our module network approach to infer the signaling network between 13 genes in the ER- α pathway in human MCF-7 breast cancer cells show that our approach gives sensible results.

For example, the Module Networks approach built a probabilistic model for the gene expression correlations between regulators and target genes and iteratively searched for the most compatible partition of targets genes to their respective regulators [ 9].

Segal et al. [ 22] have developed a module-network approach to identify modules that underlie tumourigenesis.

We compared the module network with the triplets inference approach described in Markowetz et al. (2007).

With the stage-wise HCC expression data, the proposed differential co-expression network approach resolved modules with coherent co-expression change patterns over all HCC developmental stages and even deciphered the temporal activation/dismissal of involved functions.

Those results corroborate module network inference as a robust and useful approach to gain more precise insights into miRNA function.

We then proposed a differential co-expression network approach to uncover network modules involved in HCC development.

We then proposed a differential co-expression network approach to uncover gene modules involved in HCC development.

Systems approaches, like the inference of a module network from expression data, can help to achieve this goal.

Utilizing this integrative network approach, we identified transcript co-expression modules correlated with SI and other related metabolic phenotypes in each ethnic group.

The network approach allows us to explore a set of interacting genes measured by modules or sub-networks that are involved in a complex disease like PCa.