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To compare these two approaches, we also constructed a co-expression network where each module is regulated by the single transcription factor with the most similar expression to that module (Additional file 6).
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Indeed ∼70% of the genes in the red module are regulated by the chromosome 8 locus indicating this is a key genetic driver of this subnetwork.
During harvesting, the transcripts of the COI-JAZ-MYC module were regulated in both latex and bark.
Second, it assumes that genes are organized into modules, where all members of a module are regulated by the same factors and in the same way.
While a majority of the genes in the stroma module were regulated by EMT-inducing factors, many of the stroma genes are also well known fibroblast markers.
Moreover, a significant number of genes in this module are regulated by four common transcription factors: GAT3 (p = 10-21), YAp5 (p = 10-17), pDR1 (p = 10-11), and MSN4 (p = 10-11).
In the first module, the transcription of the genes coding for degradative enzymes are regulated by TenA and TenI, while genes in the second module are regulated by SenS and DegU, which also regulate the expression of genes responsible for biofilm formation.
The position and velocity of the modules are regulated by controlling the engagement time of the clutches using the pulse width modulation technique.
The interactions among the modules were regulated by inter-modular transcription factors.
In particular, they found that the gene modules were regulated by both transcription factors and miRNAs played important roles in the pathogenesis of OLP.
This suggests that a large number of genes in the four eQTL modules are regulated in-part by each of these different eQTL hotspots.
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CEO of Professional Science Editing for Scientists @ prosciediting.com