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Target enrichment: module is enriched in known targets of the predicted regulator, module is most enriched for predicted regulator.
The black module is enriched with white matter related genes while no such enrichment can be found for the red module [ 11].
For each network module, it will be regarded to be related to OLP if the module is enriched with the above identified differentially expressed genes, where the enrichment analysis was performed with Fisher's exact test (P value cutoff of 0.01).
The red module consists of genes involved in mitochondrial function while the turquoise module is enriched for genes associated with immune response.
This module is enriched with mitochondrial related functions.
This module is enriched in genes related to a large variety of functional categories (Table 4).
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Pathway analysis revealed that the module was enriched for mitochondrial pathways (8.6-fold enrichment, P-value 4.5 × 10−72).
Pathway analysis revealed that the brown module was enriched for mitochondrial pathways (8.6-fold enrichment, FDR-adjusted Fisher Exact Test P value = 4.5 × 10−72).
The module was enriched in genes that regulate T-cell-mediated rejection (TCMR) of liver and other transplanted organs.
Table 6 shows that each module was enriched in different GO processes.
The "light yellow" module was enriched for transcripts correlated with SI only in AAs.
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