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The lack of an individual thumb module in humans may be explained by the loss of other intrinsic hand muscles.
This review will define the MAPK module in humans and model organisms, alternative MAPK signaling, pathway specificity within a MAPK module, substrates, scaffold proteins, localization, cell architecture, and signal strength.
But when the researchers created five modules that lumped together genes that were co-expressed, they found that the module in humans that's most closely tied to synapse formation and function had a "drastically" different developmental trajectory.
By far the most abundant pTyr binding module in humans is the Src Homology 2 or SH2 domain [30].
A core network module in humans and mice was identified that is enriched for genes involved in the inflammatory and immune response and was found to be causally associated to obesity-related traits [49].
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The fusiform face area: a module in human extrastriate cortex specialized for face perception.
Kanwisher, N., McDermott, J. & Chun, M. M. The fusiform face area: a module in human extrastriate cortex specialized for face perception.
Kanwisher, N., McDermott, J. & Chun, M. M. The Fusiform Face Area: A Module in Human Extrastriate Cortex Specialized for Face Perception.
Kanwisher, N., Mcdermott, J. & Chun, M. M. The fusiform face area: a module in human extrastriate cortex specialized for face perception.
When it was originally described, the salmon gene co-expression module in human CN was found to be enriched with genes that are preferentially expressed in neurons, genes that encode synaptic proteins, and genes involved in signal transduction [ 21].
In addition, based on the comparisons of the MYC-centered regulatory module and the core regulatory module in human ES cells, our results suggest that MYC acts independently of the core module in the regulation of pluripotency of human ES cells.
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