Sentence examples for module identification method from inspiring English sources

Note that our aim is not to develop a new module identification method.

We present a miRmR module identification method that facilitates better biological interpretation of high-throughput miRNA and mRNA microarray data.

We note that other clustering algorithms, e.g. a hierarchical clustering algorithm [ 16], can also be used in our module identification method.

To this end, we propose a novel miRmR module identification method that has two components - the first component is the identification of miRNA and mRNA clusters and the second component is the estimation of association between the two types of clusters.

This integrative approach allows to systematically explore functional modules in the network and it is highly complementary to existing bi-clustering and other module identification methods.

Although there are many methods for motif and motif module identification, methods that can handle all of the non-coding regions of the human genome are still in great need.

The other two module identification methods also show higher specificities than FoldChange_2.0, which suggests that the interaction data of the gene network provide additional information of cell responses at the molecular level.

We used a second data set, a timecourse study with matched miRNA and mRNA microarray expression profiles, to illustrate our module-identification method.

The miRNA clusters obtained using K = 20 for ClustUN were provided as input to Step 2 of the module-identification method.

Overall, the highest PrEnrich value was 84% corresponding to K = 50 and these 42 (0.84 × 50) mRNA clusters were used in Step 2 of the module-identification method.

As Wigwams considers every DE gene as a seed gene during the module identification stage, the method is comprehensive, but the output after the first stage is likely to have a high degree of redundancy.