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For low values of the coupling, a state of weak internal coherence within the five modules governs the coordination dynamics of the network.
There may be cases where several transcriptional modules governing the entire gene network exist and some genes belong to multiple modules.
Identifying the responsible regulatory modules that govern the coordinated actions of combinatorial transcription factors is crucial for understanding the regulatory circuits of biological processes [5].
The pleiotropic nature of the pln QTL hierarchy [14] [17] and the inferred molecular functions of the underlying candidate genes suggest that these loci represent central nodes (switches) in genetic modules that governed the reproductive phenotype of solitary ancestors before being co-opted as ontogenetic regulators of social insect phenotypic plasticity [see a review in ref. 13].
The mathematical model governing the static behavior of the module is developed using the principle of virtual work.
How does module 1 nucleate into a distinct sub-complex and what governs the association with the base on one side or module 2 on the other, were objectives of the present study.
The TCR recognition module governs MHC-Ag recognition and the association of the protein tyrosine kinase (PTK) zeta-chain-associated protein kinase of 70 kDa (ZAP70) with the intracellular immunoreceptor-tyrosine-based activation motifs (ITAMs) of CD3.
Thus the association between the chemokine receptors and LASP-1 suggests to the presence of a CXC chemokine receptor-LASP-1 pro-migratory module in cells governing the cell migration.
We show cause and effect experiments indicating that suppressive interactions among the modules govern their selection.
The inactivation kinetics of the poking-induced current reflecting the properties of the protein from which the pore module was derived (Fig. 5a, b), suggesting that the pore module governs inactivation kinetics.
It is a matrix of interoperable modules governed by design rules.
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