As shown in Figure 2, the two large modules are dominated by neuro-related signal transduction and immune related pathways, respectively.
Along these lines, amino acid compositions of all modules are dominated by polar, charged, and structure-breaking residues and depleted in hydrophobic residues relative to globular proteins.
Some genes within the adipose-magenta module, which is dominated by within-mouse variation, also have large between-mouse fold changes.
The second family, formerly known as carbohydrate-binding module 33 (CBM33), is dominated by enzymes of bacterial and viral origin but is also reported to encompass a few enzymes from eukaryotes, namely, the fungus Sporisorium reilianum and the fern Tectaria macrodonta (Carbohydrate Active Enzymes database; http://www.cazy.org) [ 2].
Since the actual PV module production is largely dominated by Si (mono, poly-crystalline, or amorphous), the enhancement of energy conversion efficiency through Si-based or Si-compatible nanostructures could lead to a breakthrough in the PV market.
We find that the rank-based network significantly differs from the value-based network in several important aspects, and we argue that the former is able to better capture the global topology of the underlying biological system, including both strongly and weakly co-expressed modules, while the latter is dominated by the most strongly co-expressed modules.
Therefore, rank-based networks can usually capture the topology of both strongly and weakly co-expressed modules, while value-based networks are often dominated by the strongly co-expressed modules.
By investigating the evolutionary profiles of the modules and their MPD/MNTD coordinates, we found that most (64%) modules with strong tree-level clustering were dominated by widely conserved genes, and that 11 modules with strong tip-level clustering were dominated by clade-specific genes.
Cluster I was dominated by acetotrophic methanogenic modules and the Clostridium-driven primary fermentation module, while the network of Cluster II was dominated by hydrogenotrophic and acetogenic methanogenesis modules and multi-group-driven (Spirochaetes, Bacteroidales, and Clostridia) primary fermentation modules.
