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Another biological process that seems to be targeted is the nuclear import/export module as evidenced by the association of Env with Importin13 (IPO13), a nuclear transport protein belonging to the importin-beta family.
It is clear here that DNA-B represents one such module, as evidenced by the relatively frequent exchange of this component for at least some of the groups of begomoviruses.
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To better understand the role of miRNAs in different biological modules, as evidenced in our cohort of primary breast cancer samples, we further take a systems biology approach to examine the correlative relationship between miRNA and mRNAs.
As a whole, students were less risk averse after completing the MathBench modules, as evidenced by a significant decrease in the frequency of "I don't know…" responses between the pre- and the posttests (F1196 = 80.578, p < 0.0001).
The gene regulatory events for two genes, DREB1A and DEAR1, in the cold-specific gene module had also been validated, as evidenced through the literature search.
Interestingly, Module 2 (enriched with Dex-induced genes) was more structured than Module 1 (predominantly Dex-repressed genes) as evidenced by consistently higher average neighborhood connectivities and average clustering coefficients.
Model A describes the intramixing within one module as well as the intermixing between neighbouring modules.
We annotated each module as follows.
Observed relationships between intron locations and protein structures (module boundaries) are used as evidence for the ancient origin of introns and for their role in exon/domain shuffling [ 20].
To lower the FDRs on those modules, additional constraints such as evidence of physical interactions between drivers and passengers are probably needed.
Investigators identified the module as handiwork of Bengali, an Indian Mujahedeen -- Qaeda-Jamaat-ul-Mujahideen Bangleader-affileader terrorist leader.
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