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The sign bit of the input is operated with either an Ex-or or comparator module based on the module activated by the operator switch.
The module activated by each GAL4 line is listed above the line name.
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MAPKs are important components of signaling modules activated by neurotransmitters, cytokines, and growth factors, as well as chemical and mechanical stressors.
Thus, elucidating the effectors and signaling modules activated by TGF-β may offer new insights into the development of novel neoadjuvants capable of effectively targeting the TGF-β pathway to significantly improve the clinical course of patients with cancer, fibrosis or immunologic disorders.
The Raf MEK1/2 ERK1/2 mitogen-activated protein kinase module is activated by stimuli complicit in mammary neoplastic progression.
Plant SCAR/WAVE- Arp2/3 module is activated by the Rop GEF SPIKE [ 164].
Each MAPK module is activated by specific types of stimuli and induces specific adaptive responses.
Which module is activated by the switch depends on, e.g., an environmental factor.
In general, each MAPK module is activated by specific types of stimuli and induces specific adaptive responses.
In these proteins, the ATP-binding module is activated by the formation of an oligomeric assembly and drives conformational changes affecting target substrates.
The Raf MEK1/2 ERK1/2 module is activated by growth factors and proteins overexpressed in human breast cancer epithelium, by cytokines and hormones produced by fibroblasts and macrophages in the mammary stromal compartment, and by increased tissue stiffness observed during tumor progression [ 10, 12].
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