Sentence examples for modulator of natural from inspiring English sources

Thus, the results from PACAP KO mice suggest a new role for PACAP as an endogenous modulator of natural Treg expansion.

Microarray analysis of miRNA expression in peripheral blood cells of SLE patients revealed that 16 miRNAs were differentially expressed in SLE [ 44]. miR-146a was identified as a negative modulator of natural immunity and low miR-146a expression was negatively correlated with clinical disease manifestation in SLE patients.

There are other studies, which demonstrate Fluconazole modulator activity of natural products.

High doses of aspirin may lead to inhibition of synthesis of natural modulators of platelet function such as the vascular prostaglandins, PGI2, PGD2 and PGE2, while recent work (see below) has shown that P2Y12 antagonists can promote the inhibitory effects of these same natural modulators of platelet function [ 62].

Within hours of their release from the bone marrow, basophils migrate from the circulation to the barrier tissues (e.g., the skin and mucosa), where they synthesize and store histamine, a natural modulator of the inflammatory response.

Thus lactic acid has the potential to be a natural modulator of APP processing and Aβ production in the brain.

The work presented here adds another dimension to the role of ENPP1, and supports the hypothesis that ENPP1 may act as a natural modulator of insulin signalling in the liver.

Intriguingly, decorin is also a natural modulator of the RDEB phenotype (Odorisio et al, 2014) and, in analogy to OI, increased TGF-β activity contributes to disease progression in RDEB.

The story for iGb3 is less clear because although it stimulates NKT cells and has been hypothesized to be a natural modulator of them, recent studies have found that the human iGb3 synthase gene contains several mutations that render its product nonfunctional (in constrast to rat, where iGb3 synthase is intact and iGb3 is found).

These compounds have an oestrogen-like structure and their use has been proposed in the treatment of the postmenopausal women as a new improved form of "natural" selective oestrogen receptor modulators (SERM).

Since GHK is present as an amino acid sequence in proteins of ECM and is released after an injury, it appears to serve as a natural built-in modulator of dermal repair.