Widespread among bacteria and archea, members of the MoxR family of AAA+ ATPases are important modulators of multiple stress tolerance pathways (Snider et al., 2006; Wong and Houry, 2012).
Associated with diverse cellular activities, MoxR ATPases display a chaperone-like function and have been found to be important modulators of multiple-stress-response pathways in various organisms, including R. leguminosarum[ 92, 93].
The delivery of IMRT with a single physical modulator for multiple fields: a feasibility study for paranasal sinus cancer.
In fact, the current investigation represents the first analysis comparing basal and modulator-induced activity of multiple distinct pathways such as Jak/Stat, PI3-kinase/Akt/S6 and the Ras/Raf/Erk/S6, phosphatase/reactive oxygen species, and DDR/apoptosis pathways in the context of FLT3 status.
The use of these metabolic modulators allows determination of multiple parameters of the mitochondrial function, as described previously [ 4, 23, 24].
Recent studies, however, have identified a potential role for alkaline phosphatase as modulator of inflammation in multiple settings, including during adult cardiopulmonary bypass.
In the present study we aim to explore the joint effects of multiple modulator genes in modulating global gene regulation and dissect the biological functions in breast cancer.
Phase masks for the 2-D SORI phase-code multiplexing can be generated by shifting an elaborately designed phase plate at a certain step, which can avoid the use of a high-cost phase spatial light modulator for the generation of multiple orthogonal phase masks.
The class IA PI3-K signaling cascade is a crucial modulator linking the activation of multiple receptor classes to many core cell processes, including cell cycle, cell survival, protein synthesis, growth, metabolism, motility, and angiogenesis, via key signaling intermediates, including the SGK and AKT families.
