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These results indicate that gelsolin functions as a modulator of lipid metabolism in fibroblast cells.
CoQ also acts as an antioxidant and is a modulator of lipid β-oxidation and apoptosis [1].
Albalat et al. [ 29] suggested that TNFa could be a key modulator of lipid metabolism in fish.
Rsad2 may act as a modulator of lipid droplet contents and lipid biosynthesis; Colec11 might play a role in apoptopic cell clearance and maintenance of adipose tissue.
While preparing this manuscript, PI binding property of Pdr16p (Sfh3p) was identified as an essential feature for function of Pdr16p as a modulator of lipid droplet neutral lipid utilization [29].
Furthermore, ATF4-deficient mice show reductions in hypertriglyceridemia induced by high fructose diets (Zhu et al., 2013) and increased insulin sensitivity (Zhang et al., 2013), suggesting that ATF4 may act as a modulator of lipid metabolism in the liver.
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Rather, the key modulators of lipid bilayers/peptide association are the peptides charge distribution and secondary conformation.
PPARs are key modulators of lipid metabolism and exhibit anti-inflammatory effects in EAE.
These data highlight the potential of this technique to be used to evaluate new pharmacological modulators of lipid metabolism.
In addition, novel metabolite protein associations were found, including known modulators of lipids and sterols in mammals, such as sphinganine, behenic acid and LysoPtCho.
As a modulator of cell membrane lipid composition, DHA can disrupt lipid rafts, thereby impairing HER2-regulated pathways and inducing cell apoptosis [ 15].
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