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On the contrary, mutations in the replication machinery proteins such as DnaA, SeqA (negative modulator of initiation of replication), and Dam (DNA adenine methyltransferase) change the phospholipid constituents [84], [85], suggesting the presence of a bidirectional regulatory system to maintain the genomic DNA and cellular membrane.
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Therefore, ethylene is not necessarily behind the loss of this capacity, but acts as a modulator of its initiation instead.
Recent studies have focused our attention on the possible role of WT SOD1 as a modulator of disease initiation.
Other modulators of translation initiation are also likely to be important in regulating gene expression in AD, in particular the eIF2alpha kinases PKR and PERK, which can, like hippuristanol, regulate translation initiation.
Moreover, we and others were able to determine Bone Morphogenetic Protein 4 (BMP7), BMP7 and TGF β as important modulators of melanoma initiation and progression (Poser et al, 2005; Rothhammer et al, 2005, 2007; Javelaud et al, 2008).
Art works became tests of initiation.
It's like a novel of initiation".
It was a kind of initiation.
That was my moment of initiation.
This gene is a transcriptional and translational regulator of mRNA, in particular acting via the phosphorylation of the elongation initiation factor (EIF4E), which is an important modulator of cell growth and proliferation [ 57].
"Fibroblast Growth Factor 9 Is a Novel Modulator of Negative Affect," from PNAS Depression is notoriously tough to handle pharmaceutically.
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