Sentence examples for modulator of bone from inspiring English sources

In bone tissues, recent studies have demonstrated that ROS generation is a key modulator of bone cell function and that oxidative status influences the pathophysiology of mineralised tissues.

Taken together these results confirm the possibility that CPPs play a role as modulator of bone cell activity, probably sustained by their ability as calcium carriers.

It is also possible that sclerostin is not the only mechanically responsive modulator of bone during unloading.

Our in vivo analyses revealed as miR-1a-3pmiR-1a-3pmiR-1a-3pa functionally important positive modulator of bone metastatic pain, indicating a pronociceptive function for miR-1a-3p.

With regards to TGF β, in physiologic conditions it acts prevalently as modulator of bone deposition, by stimulating migration, proliferation, and survival of osteoblasts, while its tumorigenic properties promote PCa cell migration and metastasis [ 105].

Besides the important endocrine modulator of bone matrix, it has been shown that supplementation with alkaline salts have significant effects on markers of bone turnover and urinary pH and net acid excretion.

Therefore, the biomechanical effects of postulated modulators of bone repair can be measured during early stages (bone formation, bridging, early consolidation) of DO in a rat model.

Thus, sex hormones are important modulators of bone mass [ 25], suggesting an effect of estrogen on trabecular bone [ 26, 27].

Proinflammatory T helper cells are now considered potent modulators of bone turnover and are important sources of osteoclastogenic cytokines under inflammatory conditions.

CCN proteins could therefore serve as potential therapeutic targets for drug development against primary and metastatic bone tumors " The CCN family proteins: modulators of bone development and novel targets in bone-associated tumors".

To our knowledge, there is no study that has examined the effects of a family-centered lifestyle intervention that investigated the altered bone structure [ 51] or modulators of bone health in addition to those that can reduce adiposity [ 52].