Sentence examples for modulator of IL7-dependent from inspiring English sources

We have shown that Gfi1 is a critical modulator of IL7-dependent B cell differentiation.

IL-15, a recognized potent positive modulator of NKG2D-dependent responses of NK cells is rendered poorly activating in the presence of Tex [65].

A23187 is a potent modulator of Ca2+-dependent processes in the parasite, including secretion of microneme proteins required for motility and invasion.

Finally, CCT2 was identified as a new modulator of p53-dependent proliferation arrested by RNAi in human cells.

The protective effect of Nrf2 induction caused by the loss of Keap1 was reduced when p65 was depleted, implying a role for p65 as a modulator of Nrf2-dependent cell protection.

Since miR-511 seems to be an important modulator of rs2734647 genotype-dependent MECP2 expression in humans, we asked whether this miR would be detectable in brain regions relevant for impulsivity and aggression (frontal and prefrontal cortex, temporal cortex, occipital cortex, hippocampus, and amygdala).

p63 acts as a selective modulator of Notch 1-dependent transcription and also transactivates the Notch ligand, JAGG-1 [16,17].

p53-upregulated modulator of apoptosis (PUMA), a BH3-only Bcl-2 family protein, is one of the most potent mediators of p53-dependent and p53-independent apoptosis induced by various stimuli.

This effort led to the discovery of BAF312 (1- 4-{1-[(E -4-cyclohexyl-3-trifluoromethylbenzyloxyimino]-ethyl}-2-ethylbenzyl -azetidine-3-carboxylic E -4-cyclohexyl-3-trifluoromethylbenzyloxyimino]-ethyl}-2-ethylbenzyl -azetidine-3-carboxylic E -4-cyclohexyl-3-trifluoromethylbenzyloxyimino]-ethyl}-2-ethylbenzyl -azetidine-3-carboxylic E -4-cyclohexyl-3-trifluoromethylbenzyloxyimino]-ethyl}-2-ethylbenzyl -azetidine-3-carboxylic E -4-cyclohexyl-3-trifluoromethylbenzyloxyimino]-ethyl}-2-ethylbenzyl -azetidine-3-carboxylic E -4-cyclohexyl-3-trifluoromethylbenzyloxyimino]-ethyl}-2-ethylbenzyl -azetidine-3-carboxylic E -4-cyclohexyl-3-trifluoromethylbenzyloxyimino]-ethyl}-2-ethylbenzyl -azetidine-3-carboxylic E -4-cyclohexyl-3-trifluoromethylbenzyloxyimino]-ethyl}-2-ethylbenzyl -azetidine-3-carboxylic E -4-cyclohexyl-3-trifluoromethylbenzyloxyimino]-ethyl}-2-ethylbenzyl -azetidine-3-carboxylic E -4-cyclohexyl-3-trifluoromethylbenzyloxyimino]-ethyl}-2-ethylbenzyl -azetidine-3-carboxylic E -4-cyclohexyl-3-trifluoromethylbenzyloxyimino]-ethyl}-2-ethylbenzyl -azetidine-3-carboxylic

Focusing on the mechanism for Rab3-dependent regulation led us to discover that Noc2 is a negative modulator of Rab3 activity and GLUT4 translocation and that it dissociates from the PM upon insulin activation and GTP loading of Rab3.

Ethanol, a modulator of TRPV1t (Lyall et al. 2005a, 2005b), at 20% and 40% enhanced the N + Bz tonic CT response in a dose-dependent manner.