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The present study was designed to investigate the possible modulator effect of melatonin on uterine estrogen and progesterone receptors in rats as well as the uterine response to oxytocin.
This reflects a given modulator effect of plasticity on both robustness and evolvability.
Wood et al. [ 34] observed significant antiangiogenic properties of ZA in vitro and in vivo, describing a modulator effect of BPs on endothelial cell migration.
Hence, the modulator effect of the diet on GIT functions has been accepted as essential for maintaining and improving the general health of the host [ 62].
This modulator effect of melatonin on the enzyme that controls the conversion from androgenic precursors to oestrogens has also been described in vivo in rats bearing DMBA-induced mammary tumours (Cos et al, 2006a).
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To investigate the modulator effects of clinical characteristics on the association between EpCAM polymorphisms of rs1126497 and prognosis, we carried out multivariate Cox proportional hazard analyses in a dominant model stratified by age, gender, smoking status, histology, TNM stage, differentiation, and adjuvant chemotherapy or radiotherapy.
Co-morbid alcohol use problem is associated with low CD4 probably mediated through immune-modulator effect of alcohol.
As alluded to above, ligand bias and probe-dependence of allosteric modulator effects at mGlu1 suggest different modes of receptor-agonist interactions; therefore, to accurately assess the pharmacology of the nine schizophrenia mutants, we employed both the endogenous agonist glutamate, as well as the synthetic orthosteric agonist (S -3,5-dihydroxyphenylglycine (DHPG).
As mentioned in a previous section, components in smoke have significant immune modulator effects (they alter the functions of T cells and B cells, macrophages, dendritic cells and neutrophils) on several acting points involving the reduction of the production of TNFα.
Although these genes are related to essential functions of breast tumor progression, they may possess relatively minor, or overtaken by other candidate modulators, effects in modulation of gene regulation.
This led to the identification of 53BP1, a p53 binding protein, as a critical modulator of the effect of Nutlin-3.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com