Sentence examples for modulation with abatacept from inspiring English sources

Costimulation modulation with abatacept slowed decline of β-cell function and improved HbA1c in recent-onset T1D.

We previously reported that costimulation modulation with abatacept administered for 2 years slowed decline of β-cell function over this period in patients with recent-onset T1D (2).

This is the first study to demonstrate the efficacy of T-cell costimulation modulation with abatacept in a population of patients with UA or very early RA.

Further lines of investigation in a larger patient population should further elucidate the synovial effects of co-stimulation modulation with abatacept.

We previously reported that 2 years of costimulation modulation with abatacept slowed decline of β-cell function in recent-onset type 1 diabetes (T1D).

Those results demonstrated that 2 years of costimulation modulation with abatacept slows the decline of β-cell function, measured by C-peptide as an index of endogenous insulin production, in recent-onset T1D.

This is the first trial to examine the impact of the modulation of T-cell co-stimulation with abatacept in patients with early RA.

In patients with RA, the selective modulation of co-stimulation on T cells with abatacept is effective in reducing chronic inflammation [ 35].

The patient also had treatment failure with abatacept and an allergic reaction to infliximab.

All patients treated with abatacept were analyzed as a group.

However, a previous study determined that treatment with abatacept alone resulted in comparable immunogenicity to abatacept plus MTX, suggesting that the impact of background MTX on immunogenicity with SC abatacept is minimal.