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Future investigations, however, are needed to assess the methodology in tumors of different origins and stages and to optimize the modulation to gain maximum therapeutic benefits and potentially reduced systematic toxicity.
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Following the predictive coding theory, we suggest that prediction relates to predictions sent down from predictive models housed in higher levels of the processing hierarchy to lower levels and attention refers to gain modulation of the prediction error signal sent up to the higher level.
Whereas prediction relates to predictions sent down from predictive models housed in higher levels of the processing hierarchy to lower levels of the hierarchy, attention refers to gain modulation of the prediction error signal sent up to the higher level via the feedforward connections.
We postulated that potent cell growth inhibitory activity relative to biochemical Aurora-A and Aurora-B modulation may be attributable to gain of off-target kinase inhibition in this sub-series, although we acknowledge that translation to more potent cellular inhibition of Aurora-A versus Aurora-A biochemical potency may also be a contributing factor.
Staying faithful to this, in the following, the term attention will be confined to refer to gain modulations and the term prediction to refer to the inferences.
The probe allowed us to gain insight into the modulation of this monomer/dimer equilibrium.
To gain insight into the modulation of apoptotic resistance in response to hypoxia in MKN45 cells, we next analysed the expression of IAP family proteins under hypoxia.
In this work, our aim was to gain insight into the modulation of Hsp90β in human articular chondrocytes and the possible outputs of an increase of this chaperone in this type of cells.
Using the same semi-on-line learning protocol as before, a linear regression from sound pressure level and modulation depth to gain was performed.
This modulation is gaining momentum since it achieves maximum bandwidth efficiency as no redundancy is transmitted.
Following from our analysis on specific and unspecific contributions to these effects, we could speculate that perhaps specific effects are related to the degree of match between the content of motor sensory predictions and the received input, whereas unspecific effects might be rather related to modulations in gain during active movements.
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