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From the aspect of regulation under modulation, regulation strength between a pair of genes can be modulated by (dependent on) expression abundance of another gene (modulator gene).
Exosomes, actively secreted in vitro and in vivo, are involved in immune system modulation, regulation of neuronal cell functions, and cancer progression.
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Polymer ligand of PDBA has a highly functionalised polyphenolic backbone, which exerts its own pharmacological effect via immune modulation and regulation of gene expression.
Activation of these intracellular receptors results in potent intestinal immune modulation including regulation and maintenance of intestinal intraepithelial lymphocytes and innate lymphoid cells, induction of the key barrier cytokine interleukin-22 and manipulation of the intestinal microbiota.
However, the involvement of their modulation in regulation of target genes by xenobiotics, including that of CYP1A1 in response to TCDD, remains relatively poorly documented.
Accumulating evidences suggest that NTs, especially Nerve Growth Factor (NGF) and Brain-Derived Neurotrophic Factor (BDNF), participate in inflammatory responses, including the modulation and regulation of immune functions in inflammatory and autoimmune diseases [2].
Despite the economical and ecological importance of bivalves, there are few reports on the description of caspase genes or the effects of different stimuli on the modulation and/or regulation of different apoptotic pathways.
STAT-1 and p21 are essential proteins that are involved in modulation and regulation of apoptotic process [ 36, 38].
PARP-1 is implicated in chromatin structure modulation, transcription regulation and double-strand break (DSB DNAA repair [ 17].
20α-HSD plays a crucial role in the modulation and regulation of steroid hormones, such as androgen, estrogen, and progestins [ 4].
Our study provides new insights into the underlying mechanisms related to modulation and regulation of various biochemical pathways in response to fungal infection.
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