Sentence examples for modulation of viral from inspiring English sources

These results highlighted the importance of certain Nef-specific CTLs in modulation of viral co-receptor down-regulation activity and protection from HIV-1 superinfection, providing us with additional insight into vaccine design.

This work is leading to clinical advances in vaccines and drug modulation of viral infections associated with cancer.

Thus, overproduction of viral attachment molecules and its resulting modulation of viral receptors may contribute to control the natural infection course of various viruses.

Modulation of viral CUPrefs with respect to the host's CUPrefs may help push the equilibrium in one direction or another.

Studies of the antiviral activity of siRNA have shown that it is effective in the inhibition of viral infection and modulation of viral replication in cultured mammalian cells.

Within our collaborative Tregitope network, we have performed a number of studies to probe potential therapeutic applications of Tregitopes in mouse models of MS (EAE), cardiac transplant, diabetes (NOD), antigen-induced airway hyper-responsiveness, and modulation of viral vector immunogenicity in adeno-associated virus (AAV -mediated gene trAAV -mediated

SK1 has recently emerged as a host factor involved in the modulation of several viral infections, having been shown to play both a positive and negative regulatory role.

Subsequent functional experiments suggest that modulation of these viral proteins by BART-encoded miRNA can influence multiple cellular properties including cell proliferation, survival, and evasion of host immune response [48]– [48].

IFIT1 is typically silent in most cells, but becomes highly expressed in response to interferons, viral infection, and certain molecular patterns, with IFIT proteins having antiviral effects through binding and modulation of host and viral proteins and RNA [ 36].

Modulation of immunogenicity using viral immune evasion strategies has become a field of active research over the past decade.

These differentially expressed ORFs include transcripts for MPXV proteins which have not previously been characterized as well as ORFs which are critical to modulation of host defenses (viral suppressors of Toll-like receptor signaling, secreted TNFα and IFNα/β decoy receptor, and IL-18 binding protein).