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We analysed rhEPO-mediated modulation of tumour cell sensitivity to apoptosis.
Successful modulation of tumour pO2 was verified by means of OxyLite probes as described below.
Biodistribution studies were also carried out in mice following modulation of tumour hypoxia.
Modulation of tumour cell growth by tumour-infiltrating leucocytes is of high importance for the biological behaviour of malignant neoplasms.
Thus, these data suggest a role for Brms1 for the modulation of tumour metastasis in response to systemic S1P signalling.
One strategy is the biochemical modulation of tumour drug resistance, an important area of experimental and clinical cancer therapeutics.
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S100A4 can also be secreted and once extracellular can affect several facets of tumour progression such as angiogenesis, stimulation of cell motility, upregulation of matrix metalloproteinases (MMPs), modulation of tumour-related transcription factors, and potentially as a stromal factor (Ambartsumian et al, 2001; Belot et al, 2002; Schmidt-Hansen et al, 2004a, 2004b).
To better understand the modulation of the tumour microenvironment induced by MSCs in response to direct interaction with T cells and cancer cells, MSCs and tumour infiltrating lymphocytes (TIL) activated by cancer cells were tested in a co-culture system that modelled the tumour microenvironment.
Further studies are warranted to assign specific roles to the different galanin receptors in the modulation of the tumour phenotype and to identify the clinical implications of the expression of galanin in NT.
Using an immuno-competent murine model of OC, we demonstrate that the reovirus+GEM combination therapy produces better cancer outcomes and that these therapeutic benefits result primarily from the augmentation of anti-tumour immune responses through the modulation of the tumour-associated immunosuppressive microenvironment.
The presence of CYP1B1 may be of importance in the modulation of these tumours to anti-cancer drugs.
More suggestions(16)
manipulation of tumour
variation of tumour
alteration of tumour
alignment of tumour
modification of tumour
preparation of tumour
transformation of tumour
diversity of tumour
modulation of sunspot
modulation of brain
modulation of grip
modulation of pain
modulation of voice
modulation of inflammation
modulation of music
modulation of activity
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