Sentence examples for modulation of tumorigenesis from inspiring English sources
Finally, we discuss briefly the potential roles of DUSPs in the regulation of non-MAP kinase targets, as well as in the modulation of tumorigenesis.
The dysregulation of the EMT and the altered MASPIN, NDRG1, and KAI1 gene expression induced by IL6 may lead to the modulation of tumorigenesis in bladder carcinoma cells.
Growing evidence indicates that tumor-derived microvesicles are involved in tumor progression via the modulation of tumorigenesis, angiogenesis, immune response, invasion, and metastasis [ 1- 5].
P62 is not only involved in the autophagy targeting of ubiquitinated protein aggregates but also plays a role in autophagy-mediated degradation of ubiquitinated-labelled peroxisomes (Kim et al., 2008b) and the autophagy modulation of tumorigenesis.
Our results suggest that the effects of interleukin-6 on the regulation of epithelial-mesenchymal transitions and the expressions of the MASPIN, NDRG1, and KAI1 genes attribute to the modulation of tumorigenesis in human bladder carcinoma cells.
These data further support the fact that several sPLA2s may contribute to the initiation, progression or modulation of colon tumorigenesis, and may provide new potential tumour markers for this disease.
The involvement of this potentially oncogenic lncRNA with the modulation of RASSF1A and tumorigenesis in cancer patients has not been studied, and further work is warranted.
Conceivably, interferon-γ could contribute to the suppression of tumorigenesis indirectly, through modulation of the immune system, as well as directly by exerting anti-proliferative and pro-apoptotic effects.
The overexpression of NRP-1 has been shown to regulate not only angiogenesis, but also other aspects of tumorigenesis, such as modulation of apoptosis and cell migration in human colon cancer [ 23], epithelial-mesenchymal transition of human ovarian cancer, [ 24] and especially tumour-induced immune tolerance [ 25].
In this study we explored progestin modulation of miRNA expression in mammary tumorigenesis.
These findings imply that DCD promotes breast tumorigenesis via modulation of ERBB signaling pathways.
