Sentence examples for modulation of the cell cycle from inspiring English sources

These data showed that RITA and nutlin3a differentially modulated the cell cycle and that RITA induced a similar modulation of the cell cycle in TP53 wt and TP53 mutated HMCLs.

These off-target effects involve induction of autophagy and necrotic cell death as well as modulation of the cell cycle and multiple cell signaling pathways.

Apoptosis and cell cycle detection suggested that only phenanthrene affected cell cycle significantly and caused cell death; GTP lowered the mortality of HFL-I cexposedposed to phenanthrene; However, GTP did not affect modulation of the cell cycle by phenanthrene.

The intricate spatial regulation of cell proliferation and differentiation within the meristem almost certainly involves modulation of the cell cycle machinery in the various SAM domains.

The activation of these pathways in combination with the modulation of the cell cycle and cell communication activity (cluster 4) seem to be the phenotypic consequences to TGF-β stimulation of HaCaT cells.

We also believe the perturbation has also influenced NF-kB signalling and resulted in a modulation of the cell cycle.

Indeed, a previous study using green tea polyphenol diet to treat A/J mice bearing the NNK-induced lung tumor for 20 weeks, a long term treatment, also revealed the modulation on the cell cycle: a group of 88 genes were identified as the responsive genes and a major associated network of these 88 genes was the cell cycle regulation [ 21].

The current study examined the effect of these xanthones on the modulation of the cell cycle-related gene expression in SK-MEL-28 cells.

Moreover, TRPM7 is required for proliferation of the cancer cells as evidenced by the cellular assays and modulation of the cell-cycle regulators, and TRPM7-mediated proliferation of pancreatic adenocarcinoma cells is Mg2+-dependent.

Modulation of the cell-cycle pathway may be a novel approach to reduce activated/memory-resistant and apoptosis-resistant pathogenic T cells and B cells, and to ameliorate systemic autoimmunity.

Recent studies revealed that the anticancer activity of herbal medicines was linked to modulation of apoptotic signaling, the cell cycle, angiogenic factors, invasion, and metastatic events in cancer cells [ 16- 19].