Sentence examples for modulation of substrate from inspiring English sources

Actually, this modulation of substrate temperature directly influences the solvent evaporation rate.

For precise modulation of substrate functions by calpains, the cleavage sites are anticipated to be strictly determined depending on substrates [15].

The genetic modulation of substrate utilization similarly exhibit divergent effects.

However, the modulation of substrate specificity makes it difficult to define the physiological function based only on the sequence.

Regulation of APC/C activity and modulation of its substrate specificity are subject to intricate cell cycle checkpoints and control mechanisms involving the switching of substrate-specifying cofactors, association of regulatory protein complexes and post-translational modifications.

Pharmacological strategies for the modulation of target substrate degradation are also reviewed, with emphasis on their in vivo implications.

Modulation of the substrate specificity of enzymes of this complex pathway is therefore likely to enable metabolic engineering efforts of these alkaloids.

The crystal structure of Rauvolfia serpentina strictosidine synthase (STR1) in complex with strictosidine has been elucidated here, allowing the rational site-directed mutation of the active center of STR1 and resulting in modulation of its substrate acceptance.

Aspects of mitochondrial function that have been manipulated to investigate this include: modulation of energy substrate utilization; activation of mitochondrial biogenesis; induction of mitochondrial antioxidant defenses and suppression of mitochondrial death programs including apoptosis and mitochondrial permeability transition.

However, a specific physiologic trigger (e.g., increased adrenergic tone) promoting ventricular ectopy or further modulation of the substrate by inflammatory processes may be required to increase the probability of a clinically important arrhythmic event.

- Although the regulation of intracellular phosphoinositide profiles by other lipid phosphatases, including phosphatase and tensin homolog (PTEN) and inositol polyphosphate-5-phosphatase 1, are well characterized, little is known about the modulation of target substrates by INPP4B.