Sentence examples for modulation of stem from inspiring English sources

This article also reviews artificial ECMs used for modulation of stem cell behaviors for tissue engineering applications.

The use of small specific molecules has been instrumental in the modulation of stem cell proliferation and differentiation to obtain insulin-containing cells.

This chapter describes methods for the design, development, and implementation of cell‐based screens of small molecules, genes and expressed proteins for modulation of stem and progenitor cell fate.

Modulation of stem cell behavior holds exceptional promise for a new prophylactic approach for controlling mammary cancer risk.

The stem cell niche may represent a significant entry point for therapeutic modulation of stem cell behavior [ 7, 8].

This occurs through modulation of stem cell self-renewal and inhibition of genes promoting cellular differentiation [ 8].

Recent research demonstrate that ageing, and longevity are also governed by genetical processes [1] which have been shown to consist of several factors, such as mitochondrial mutations, modulations of stem cell developmental pathways and immunosenescence [2], [3].

Our results provide insights into a novel PVF2-mediated mechanism for age-related modulation of intestinal stem populations and suggest that oxidative stress is likely to contribute significantly to age-related changes in intestinal stem cell biology.

Future work in regenerative medicine may be able to capitalize on Vmem as a powerful and tractable control point for rational modulation of adult stem cell function.

However, little is known about the underlying molecular mechanisms that link aging to the modulation of adult stem cell populations.

In particular, we will highlight some of the complexities of the system, but also where there may be therapeutic potential for modulation of intrinsic stem cells and where particular caution may be needed in terms of cell transplantation therapies.