Sentence examples for modulation of selected from inspiring English sources

In mammalian cells, MAP4K3 enhances the mitochondrial apoptosis pathway through the post-transcriptional modulation of selected proapoptotic Bcl-2 homology domain 3-only proteins.

To gain knowledge about the effects of IL-17 in SFCs of patients with RA, we studied the expression and modulation of selected genes differentially expressed after stimulation with IL-17.

We describe a procedure for controlled, periodic, reversible modulation of selected regions of the blood brain barrier (BBB) or the inner-blood retina barrinner-blood retinan incorporation into an AAV-2/9 vector of a doxycycline-inducibarriere encodiBRBshRNA targeting claudin-5, one of 30 or so proteins constituting the basednd iBRB.

To exclude that these observations could be due to nonspecific off-target effects, CHKA-specific silencing and co-modulation of selected genes were validated by RT-qPCR using a second independent CHKA-specific siRNA pool (Supplementary Figure 5A and 5B).

HIV can even manipulate the expression of host neuronal genes, such as SNAP25 and cell death-related genes, including caspase-6, via the modulation of expression of selected microRNAs, which might serve as key elements in gene regulatory networks in HIV-associated neurobehavioral disorder [ 19- 21].

Thus, the determination of individual gene expression patterns may facilitate the selection of the best medication or, more ambitiously, may allow directed modulation of (individually) selected pathways/complexes instead of broad suppression of inflammation by anti-inflammatory/anti-rheumatic drugs [ 84].

In order to analyze the mechanisms of protection of probiotic-pulsed BMDCs in TNBS-induced colitis, the modulation of the expression of selected genes was assessed in the animal colons by real time PCR using the Taq-Man qRT-PCR technology.

The BS then broadcasts the indices of selected users with appropriate modulation and coding schemes level.

Several impaired cellular function were reversed by iloprost treatment and the gene array modulation was validated by quantitative RT-PCR of selected genes.

We paid particular attention to pharmacologically-relevant approaches exploiting the modulation of niche-associated factors and the application of selected small molecules.

To identify the immune cell subset that conferred CD4-down modulation of BT-061 decorated T cells, co-incubation experiments were performed either with PBMC depleted of selected immune cell subsets, or with the respective MACS-enriched immune cell subsets.