Sentence examples for modulation of receptor from inspiring English sources
A possible function of the oligomerization of the GABAB heterodimer is modulation of receptor signalling.
PA mediated signal transduction includes modulation of receptor signalling, cytoskeleton rearrangement, secretion, and vesicle trafficking during endocytosis or exocytosis [1].
This investigation was undertaken to determine if the functional changes observed could be attributed to peptide binding interaction with the α7-nAChR, or peptide modulation of receptor expression.
As for the effects of anandamide that are mediated by its well-characterized protein receptors such as CB1 [8], cholesterol could exert two distinct (yet not mutually exclusive) functions: i) modulation of receptor conformation with an impact on ligand binding efficiency, and ii) facilitation of the transfer of anandamide to the protein receptor following its insertion into the membrane.
Modulation of receptor trafficking is critical for controlling neurotransmission.
Modulation of receptor activity is a critical step for TGF-β signaling regulation.
The allosteric modulation of receptors has become a widely accepted concept in order to enhance the agonist or antagonist binding to a receptor.
Such neuronal plastic changes involve activation of excitatory amino acid receptors, the subsequent intracellular cascades including translocation and activation of PKC as well as nitric oxide production, leading to the functional modulation of receptor-ion channel complexes (e.g. the desensitization of μ-opioid receptor) [ 4, 5, 7– 16].
The selenoprotein thioredoxin reductase 1 (Treduceseduces the active site of thioredoxin 1 (Trx1) using NADPH and is thereby required for the many actions of reduced Trx1, including the promotion of cell viability and proliferation or the regulation of signaling pathways through modulation of receptor-linked protein phosphorylation cascades.
Its title revealed a program of research based on the specific modulation of receptors by organic molecules, the behavior of which in the body could be monitored, understood, and exploited.
We believe that aromatic tuning has several advantages compared to previous methods aimed at stimulus-independent modulation of receptors and that it will be generally applicable to a wide-range of two-component circuits.
