Sentence examples for modulation of proliferative from inspiring English sources

Genes coding for other receptor tyrosine kinases, including the platelet-derived growth factor receptor (PDGFRA) and the proto-oncogene (MET), are amplified to various degrees in GBMs, resulting in the modulation of proliferative and survival pathways [17,18].

Although this generic model has been relatively undisputed, mechanisms must exist that allow for modulation of the proliferative properties of HSC.

Thus, the mechanism that COUP-TFII promotes tumor progression and metastasis is not limited to its modulation of anti-proliferative effects of TGF-β signaling.

The modulation of human lymphocyte proliferative responses was demonstrated with a recombinant outer surface protein A (OspA) vaccine preparation for the prevention of Borrelia burgdorferi infection.

It has been speculated that the potential beneficial effects of olive oil could be due to modulation of genes involved in proliferative, antioxidant and inflammatory pathways.

In developing breast neoplasia, modulation of Hsp-27 in early proliferative lesions (O'Neill et al, 2003) occurs synchronously with that of ER-alpha to predict subsequent development of breast malignancy (P<0.001).

Such results support a number of existing models of PH where mitochondrial dysregulation can trigger a pro-proliferative phenotype via modulation of oxidative stress, cellular growth factors, and cellular survival (Cottrill & Chan, 2013).

In view of the marked paucity in effective therapeutic modalities for non-proliferative AMD, pharmacological modulation of CD36 activity may be a potential approach for this form of maculopathy.

This transcriptional pattern closely mirrors the pattern observed during the β-cell hypertrophy typically associated with pregnancy, suggesting these genes are part of a common proliferative response associated with modulation of β-cell mass in physiological and pathophysiological states.

Proliferative retinopathy usually requires treatment with laser photocoagulation akin to the treatment of proliferative diabetic retinopathy [6].

To profile vitreous cytokine expression of proliferative vitreoretinopathy (PVR) patients.