Ferenczi, E.A. et al. Optogenetic approaches addressing extracellular modulation of neural excitability.
Treating neurodegenerative disorders by non-invasive modulation of neural networks is an intriguing prospect.
Strombach, T. et al. Social discounting involves modulation of neural value signals by temporoparietal junction.
Lesch, K. P. & Waider, J. Serotonin in the modulation of neural plasticity and networks: implications for neurodevelopmental disorders.
In the past decades, increasing amount of studies has characterized the mechanisms underlying experience-dependent modulation of neural circuits.
Most FUS research is concentrated on its utility for transcranial modulation of neural structures and ablation of tissues.
These methods allow non-invasive and safe modulation of neural processes in the healthy brain, enabling researchers to directly study how experimentally altered neural activity causally affects behavior.
The pathological effect of chronic mitochondrial dysfunction on cognitive function is well established, however the acute modulation of neural processing by mitochondrial signalling is less well understood.
This upregulation may take the form of a spatially non-specific gain modulation of neural responses in early visual cortex, leading to increased neural responses at all locations where a stimulus is presented.
According to the former theory, nasal stimulation could have modified the subjects' state of consciousness through the modulation of neural electrical activity as shown by the modification of EEG features both in temporal and spatial domains.
Lieber plans to use the funding from the NIH Pioneer Award to continue to develop the capabilities of the syringe-injectable mesh electronics for stable monitoring and modulation of neural circuitry.
