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Yeagle, P. L. Modulation of membrane function by cholesterol.
Sheetz, M. P. & Dai, J. Modulation of membrane dynamics and cell motility by membrane tension.
The present results further support and extend the knowledge about the mechanism of action for 2OHOA, based on the regulation of the membrane lipid composition and structure and subsequent modulation of membrane protein-associated signaling.
These computational studies are helping to link specific component processes (e.g., changes in protein levels and phosphorylation, modulation of membrane conductances, synaptic plasticity, and network architecture) to features of nonassociative and associative learning.
In this review, after a short historical preface, we describe the current model of chemosensory transduction based on the modulation of membrane K+ channels by O2 in specialized chemoreceptor cells.
Allosteric modulation of membrane receptors has been intensively studied in the past three decades and is now considered to be an important indirect mechanism for the control of receptor function.
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Overall, the results presented here show that lipid modulation of membrane-dependent antigens impacts immunogenicity and elicits potent antibody titers.
Huarte, N., Lorizate, M., Kunert, R. & Nieva, J. L. Lipid modulation of membrane-bound epitope recognition and blocking by HIV-1 neutralizing antibodies.
Huarte, N., Lorizate, M., Kunert, R. & Nieva, J.L. Lipid modulation of membrane-bound epitope recognition and blocking by HIV-1 neutralizing antibodies.
The results indicate that the in vivo activation of adrenoceptors by desipramine is associated with a time-dependent modulation of membrane-associated GRK 2/3 (i.e. an acute increase in the kinase content which is followed by a return to the basal expression upon repeated treatment).
PAKs are also involved in the modulation of endosomal membrane transport, membrane ruffling, filopodia and lamellipodia formation (Szczepanowska, 2009).
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